PY3011 DRUGS THROUGH BIOTECHNOLOGY SYLLABUS | ANNA UNIVERSITY BTECH PHARMACEUTICAL 8TH SEMESTER SYLLABUS REGULATION 2008 2011 2012-2013 BELOW IS THE ANNA UNIVERSITY 8TH SEMESTER B.TECH PHARMACEUTICAL dEPARTMENT SYLLABUS, TEXTBOOKS, REFERENCE BOOKS,EXAM PORTIONS,QUESTION BANK,PREVIOUS YEAR QUESTION PAPERS,MODEL QUESTION PAPERS, CLASS NOTES, IMPORTANT 2 MARKS, 8 MARKS, 16 MARKS TOPICS. IT IS APPLICABLE FOR ALL STUDENTS ADMITTED IN THE YEAR 2011 2012-2013 (ANNA UNIVERSITY CHENNAI,TRICHY,MADURAI, TIRUNELVELI,COIMBATORE), 2008 REGULATION OF ANNA UNIVERSITY CHENNAI AND STUDENTS ADMITTED IN ANNA UNIVERSITY CHENNAI DURING 2009
PY3011 DRUGS THROUGH BIOTECHNOLOGY
UNIT I GENETIC ENGINEERING 9
Recombinant DNA Technology – Aims – Genetic engineering applications – Genetic
engineering tools – General techniques of genetic engineering – Transformation and
analysis of recombinants.
UNIT II VECTORS 9
Design of Plasmid vectors – Bacteriophage vectors – Cosmids – Eukaryotic vectors –
Genomic and DNA Libraries – Screening procedures.
UNIT III IMMUNOGLOBULINS 9
Antigens – Adjuvants – Monoclonal antibodies – Hybridoma cells – Applications of
monoclonal antibodies – Idiotypic antibodies – Enzymes linked immuno-sorbant assay –
Radiimmuno assay.
L T P C
3 0 0 3
77
UNIT IV IMMUNOTHERAPY 9
Vaccine technology – DNA based vaccines – Pathogenesis of infections microorganism
– Antobody Engineering – Applications – Catalytic antibodies – Humanised monoclonal
antibodies.
UNIT V GENE THERAPY 9
Strategies – Future scope – Potential – Recent developments in biopharmaceuticals –
Production through biotechnology – Geneome-based medicine – Molecular modeling –
Drug designing.
TOTAL: 45 PERIODS
TEXT BOOKS
1. Taybor, J.M., “Genetic Engineering Technology in Industrial Pharmacy –
Principles and Applications”, Marcel Dekker, 1989.
2. De Roberts, E.D.P. and De Robers, E.M.F., “Cell and Molecular Biology”, 8th
Edition, Lea and Febiger, 1987.
REFERENCES
1. Trevan, M.D., Boffey, S., Goulding, K.H. and Stan Burg, P., “Biotechnology: The
Biological Principles”, Tata McGraw Hill, 1987.
2. Rehin, H.J. and Reed, G., “Biotechnology – A Comprehensive Treatise”, Verlag
Chemic, 1983.
3. Manfred, E.W., “Burger’s Medicinal Chemistry and Drug Discovery”, Vol.I, John
Wiley, 1995.
PY3011 DRUGS THROUGH BIOTECHNOLOGY
UNIT I GENETIC ENGINEERING 9
Recombinant DNA Technology – Aims – Genetic engineering applications – Genetic
engineering tools – General techniques of genetic engineering – Transformation and
analysis of recombinants.
UNIT II VECTORS 9
Design of Plasmid vectors – Bacteriophage vectors – Cosmids – Eukaryotic vectors –
Genomic and DNA Libraries – Screening procedures.
UNIT III IMMUNOGLOBULINS 9
Antigens – Adjuvants – Monoclonal antibodies – Hybridoma cells – Applications of
monoclonal antibodies – Idiotypic antibodies – Enzymes linked immuno-sorbant assay –
Radiimmuno assay.
L T P C
3 0 0 3
77
UNIT IV IMMUNOTHERAPY 9
Vaccine technology – DNA based vaccines – Pathogenesis of infections microorganism
– Antobody Engineering – Applications – Catalytic antibodies – Humanised monoclonal
antibodies.
UNIT V GENE THERAPY 9
Strategies – Future scope – Potential – Recent developments in biopharmaceuticals –
Production through biotechnology – Geneome-based medicine – Molecular modeling –
Drug designing.
TOTAL: 45 PERIODS
TEXT BOOKS
1. Taybor, J.M., “Genetic Engineering Technology in Industrial Pharmacy –
Principles and Applications”, Marcel Dekker, 1989.
2. De Roberts, E.D.P. and De Robers, E.M.F., “Cell and Molecular Biology”, 8th
Edition, Lea and Febiger, 1987.
REFERENCES
1. Trevan, M.D., Boffey, S., Goulding, K.H. and Stan Burg, P., “Biotechnology: The
Biological Principles”, Tata McGraw Hill, 1987.
2. Rehin, H.J. and Reed, G., “Biotechnology – A Comprehensive Treatise”, Verlag
Chemic, 1983.
3. Manfred, E.W., “Burger’s Medicinal Chemistry and Drug Discovery”, Vol.I, John
Wiley, 1995.
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