ML3004 BIOMEDICAL MATERIALS SYLLABUS | ANNA UNIVERSITY BE MATERIALS SCIENCE AND ENGINEERING 8TH SEMESTER SYLLABUS REGULATION 2008 2011 2012-2013 BELOW IS THE ANNA UNIVERSITY 8TH SEMESTER B.E MATERIALS SCIENCE ENGINEERING DEPARTMENT SYLLABUS, TEXTBOOKS, REFERENCE BOOKS,EXAM PORTIONS,QUESTION BANK,PREVIOUS YEAR QUESTION PAPERS,MODEL QUESTION PAPERS, CLASS NOTES, IMPORTANT 2 MARKS, 8 MARKS, 16 MARKS TOPICS. IT IS APPLICABLE FOR ALL STUDENTS ADMITTED IN THE YEAR 2011 2012-2013 (ANNA UNIVERSITY CHENNAI,TRICHY,MADURAI, TIRUNELVELI,COIMBATORE), 2008 REGULATION OF ANNA UNIVERSITY CHENNAI AND STUDENTS ADMITTED IN ANNA UNIVERSITY CHENNAI DURING 2009
ML3004 BIOMEDICAL MATERIALS LT P C
3 0 0 3
OBJECTIVES
Students are learning medical and biomedical applications of materials. Biocompatibility
UNIT I BIOLOGICAL PERFORMANCE OF MATERIALS 9
Biofunctionality and biocompatibility - material response - deformation and failure -
friction and wear -Host response-Inflammatory process-capsule formation -
coagulationand hemolysis - approach to thromboresistant material developmentchemical
and foreign body carcinogenesis.
UNIT II ORTHOPAEDIC MATERIALS 9
Materials for bone and joint replacement-cemented and cementless total joint
replacement- metals and alloys; stainless steel, cobalt based alloys, titanium based
materials -ceramics - bioinert ceramics -carbon, alumina, zircona and titania -bioactive
ceramics -bioactive glass and glass ceramics, calcium phosphate ceramics - polymers,
grouting materials – PMMA bone cement, articulating component–UHMWPE
composites, matrix and filler components -mechanical properties.
UNIT III DENTAL AND CARDIOVASCULAR MATERIALS 9
Dental restorative materials - dental cements – zinc oxide and phosphate cements -
Dental composite materials - polymer/ceramic composites –composite component,
polymerization, properties – glass isomer cements
cement components; setting reaction,structure and properties - dental amalgams:
composition, microstructure, physical properties and degradation process -
cardiovascular prostheses: vascular -graft materials, cardiac valve Prostheses, cardiac
assist devices and cardiac pacemakers.
UNIT IV ARTIFICIAL ORGANS AND OTHER MATERIALS 9
Artificial kidney and urological prostheses ~Blood-gas exchangers - artificial pancreas -
structure and use of collagen -material for skin and nerve regeneration -collagen/GAG
graftcopolymers -tissue adhesives-fibrin and cyanoacryllc tissue adhesives-materials for
Ophthalmology - contact lens and intraocular lens materials-materials for drug delivery.
UNIT V MATERIALS CHARACTERIZATION TECHNIQUES 9
Electron microscopic methods - SEM, TEM, spectroscopic methods -IR; visible, UV and
x-ray methods, differential thermal analysis, differential thermogravimetric analysis,
NDTmethods.
TOTAL : 45 PERIODS
TEXT BOOKS
1. Sujata V., Bhat.,“ Biomaterials”, Narosa Publication House, New Delhi, 2002
2. Ratner, B.D, Hoffman,A. S., Sckoen,F.J. and Emons, J.E.L. (Eds),“ Biomaterials
Science, An Introduction to Materials in Medicine”, Academic Press, second edition,
2004.
REFERENCES
1. Jonathan Black,“ Biological Performance of materials, Fundamentals of
Biocompatibility”, Marcel Dekker Ind., New, York, 1992.
2. Williams, D. F., (editor),“ Material Science and Technology -A comprehensive
treatment”, Vol. 14, Medical and Dental Materials, VCH Publishers Inc.; New York,
1992.
3. Davis, J. R.,“ Handbook of Materials for Medical Devices”, ASM international, 2003.
ML3004 BIOMEDICAL MATERIALS LT P C
3 0 0 3
OBJECTIVES
Students are learning medical and biomedical applications of materials. Biocompatibility
UNIT I BIOLOGICAL PERFORMANCE OF MATERIALS 9
Biofunctionality and biocompatibility - material response - deformation and failure -
friction and wear -Host response-Inflammatory process-capsule formation -
coagulationand hemolysis - approach to thromboresistant material developmentchemical
and foreign body carcinogenesis.
UNIT II ORTHOPAEDIC MATERIALS 9
Materials for bone and joint replacement-cemented and cementless total joint
replacement- metals and alloys; stainless steel, cobalt based alloys, titanium based
materials -ceramics - bioinert ceramics -carbon, alumina, zircona and titania -bioactive
ceramics -bioactive glass and glass ceramics, calcium phosphate ceramics - polymers,
grouting materials – PMMA bone cement, articulating component–UHMWPE
composites, matrix and filler components -mechanical properties.
UNIT III DENTAL AND CARDIOVASCULAR MATERIALS 9
Dental restorative materials - dental cements – zinc oxide and phosphate cements -
Dental composite materials - polymer/ceramic composites –composite component,
polymerization, properties – glass isomer cements
cement components; setting reaction,structure and properties - dental amalgams:
composition, microstructure, physical properties and degradation process -
cardiovascular prostheses: vascular -graft materials, cardiac valve Prostheses, cardiac
assist devices and cardiac pacemakers.
UNIT IV ARTIFICIAL ORGANS AND OTHER MATERIALS 9
Artificial kidney and urological prostheses ~Blood-gas exchangers - artificial pancreas -
structure and use of collagen -material for skin and nerve regeneration -collagen/GAG
graftcopolymers -tissue adhesives-fibrin and cyanoacryllc tissue adhesives-materials for
Ophthalmology - contact lens and intraocular lens materials-materials for drug delivery.
UNIT V MATERIALS CHARACTERIZATION TECHNIQUES 9
Electron microscopic methods - SEM, TEM, spectroscopic methods -IR; visible, UV and
x-ray methods, differential thermal analysis, differential thermogravimetric analysis,
NDTmethods.
TOTAL : 45 PERIODS
TEXT BOOKS
1. Sujata V., Bhat.,“ Biomaterials”, Narosa Publication House, New Delhi, 2002
2. Ratner, B.D, Hoffman,A. S., Sckoen,F.J. and Emons, J.E.L. (Eds),“ Biomaterials
Science, An Introduction to Materials in Medicine”, Academic Press, second edition,
2004.
REFERENCES
1. Jonathan Black,“ Biological Performance of materials, Fundamentals of
Biocompatibility”, Marcel Dekker Ind., New, York, 1992.
2. Williams, D. F., (editor),“ Material Science and Technology -A comprehensive
treatment”, Vol. 14, Medical and Dental Materials, VCH Publishers Inc.; New York,
1992.
3. Davis, J. R.,“ Handbook of Materials for Medical Devices”, ASM international, 2003.
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