PY3403 PHARMACEUTICAL BIOTECHNOLOGY SYLLABUS | ANNA UNIVERSITY B.TECH PHARMACEUTICAL 7TH SEM SYLLABUS REGULATION 2008 2011 2012-2013 BELOW IS THE ANNA UNIVERSITY SEVENTH SEMESTER B.TECH PHARMACEUTICAL DEPARTMENT SYLLABUS, TEXTBOOKS, REFERENCE BOOKS,EXAM PORTIONS,QUESTION BANK,CLASS NOTES, IMPORTANT 2 MARKS, 8 MARKS, 16 MARKS TOPICS. IT IS APPLICABLE FOR ALL STUDENTS ADMITTED IN THE YEAR 2011 2012-2013 (ANNA UNIVERSITY CHENNAI,TRICHY,MADURAI,TIRUNELVELI,COIMBATORE), 2008 REGULATION OF ANNA UNIVERSITY CHENNAI AND STUDENTS ADMITTED IN ANNA UNIVERSITY CHENNAI DURING 2009
PY3403 PHARMACEUTICAL BIOTECHNOLOGY
UNIT I FERMENTATION TECHNOLOGY 12
Industrial fermentation processes and products – Role of bioprocess engineer – Unit
operations in an integrated bioprocess – Process flowsheet – Survey of organisms –
Processes – Products – Market economics of modern industrial biotechnology.
UNIT II RAW MATERIALS FOR FERMENTATION PROCESS 12
Isolation of microorganisms – Preservation and improvement of industrial
microorganisms for overproduction of primary and secondary metabolites – Medium
requirements for fermentation process – Carbon, nitrogen, minerals, vitamins, and other
nutrients – Simple and complex media.
UNIT III PRIMARY METABOLITES 12
Primary metabolite – Methods for the production of citric acid – Itaconic acid – Lactic
acid-Acetic acid – Gluconic acid – Tartaric acid .
UNIT IV SECONDARY METABOLITES 12
Production of low molecular weight secondary metabolites – Penicillins –
Cephalosporins -Streptomycin – Kanamycin – 1,2-benzoquinones – Ciprofloxacin –
Gatifloxacin.
UNIT V PRODUCTION AND CONTROL OF BIOTECH DERIVED
PRODUCTS 12
Recombinant DNA products – Insulin – Growth hormones – Erythropoietin – Cytokines –
Diagnostic proteins – Protein A – Protein G – Antibodies.
TOTAL: 60 PERIODS
TEXT BOOKS
1. Stanbury, P.F., Whitaker, A. and Hall, S.J., “Principles of Fermentation
Technology”, 2nd Edition, Aditya Books (P) Ltd, 1995.
2. Shuler, M.L. and Kargi, F., “Bioprocess Engineering Basic Concepts”, 2nd
Edition, Prentice Hall of India, 2004.
REFERENCES
1. Purohit, S.S., Saluja, A.K. and Kulkarni, H.N., “Pharmaceutical Microbiology”, 1st
Edition, Agrobios (India), 2003.
2. Hugo, W.B. and Russel, A.D., “Pharmaceutical Microbiology”, 6th Edition,
Blackwell Science, 2003.
3. Casida Jr, L.E., “Industrial Microbiology”, 2nd Edition, Wiley Eastern Ltd, 1968.
PY3403 PHARMACEUTICAL BIOTECHNOLOGY
UNIT I FERMENTATION TECHNOLOGY 12
Industrial fermentation processes and products – Role of bioprocess engineer – Unit
operations in an integrated bioprocess – Process flowsheet – Survey of organisms –
Processes – Products – Market economics of modern industrial biotechnology.
UNIT II RAW MATERIALS FOR FERMENTATION PROCESS 12
Isolation of microorganisms – Preservation and improvement of industrial
microorganisms for overproduction of primary and secondary metabolites – Medium
requirements for fermentation process – Carbon, nitrogen, minerals, vitamins, and other
nutrients – Simple and complex media.
UNIT III PRIMARY METABOLITES 12
Primary metabolite – Methods for the production of citric acid – Itaconic acid – Lactic
acid-Acetic acid – Gluconic acid – Tartaric acid .
UNIT IV SECONDARY METABOLITES 12
Production of low molecular weight secondary metabolites – Penicillins –
Cephalosporins -Streptomycin – Kanamycin – 1,2-benzoquinones – Ciprofloxacin –
Gatifloxacin.
UNIT V PRODUCTION AND CONTROL OF BIOTECH DERIVED
PRODUCTS 12
Recombinant DNA products – Insulin – Growth hormones – Erythropoietin – Cytokines –
Diagnostic proteins – Protein A – Protein G – Antibodies.
TOTAL: 60 PERIODS
TEXT BOOKS
1. Stanbury, P.F., Whitaker, A. and Hall, S.J., “Principles of Fermentation
Technology”, 2nd Edition, Aditya Books (P) Ltd, 1995.
2. Shuler, M.L. and Kargi, F., “Bioprocess Engineering Basic Concepts”, 2nd
Edition, Prentice Hall of India, 2004.
REFERENCES
1. Purohit, S.S., Saluja, A.K. and Kulkarni, H.N., “Pharmaceutical Microbiology”, 1st
Edition, Agrobios (India), 2003.
2. Hugo, W.B. and Russel, A.D., “Pharmaceutical Microbiology”, 6th Edition,
Blackwell Science, 2003.
3. Casida Jr, L.E., “Industrial Microbiology”, 2nd Edition, Wiley Eastern Ltd, 1968.
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