CH3405 TECHNOLOGY OF FINE CHEMICALS AND BULK DRUGS SYLLABUS | ANNA UNIVERSITY B.TECH PHARMACEUTICAL 7TH SEM SYLLABUS REGULATION 2008 2011 2012-2013 BELOW IS THE ANNA UNIVERSITY SEVENTH SEMESTER B.TECH PHARMACEUTICAL DEPARTMENT SYLLABUS, TEXTBOOKS, REFERENCE BOOKS,EXAM PORTIONS,QUESTION BANK,CLASS NOTES, IMPORTANT 2 MARKS, 8 MARKS, 16 MARKS TOPICS. IT IS APPLICABLE FOR ALL STUDENTS ADMITTED IN THE YEAR 2011 2012-2013 (ANNA UNIVERSITY CHENNAI,TRICHY,MADURAI,TIRUNELVELI,COIMBATORE), 2008 REGULATION OF ANNA UNIVERSITY CHENNAI AND STUDENTS ADMITTED IN ANNA UNIVERSITY CHENNAI DURING 2009
CH3405 TECHNOLOGY OF FINE CHEMICALS AND BULK DRUGS
UNIT I INTRODUCTION OF FINE CHEMICALS AND BULK DRUGS 12
Concept of fine and Bulk drugs and their salient features – Evolution of process –
Process chemistry – Research and development strategies in pharmaceutical industries.
UNIT II PRODUCTION, PLANNING AND CONTROL 12
Flow sheets – Types of flow sheets – Flow symbols – Line symbols – Concept of all
purpose and multipurpose plants – Plant design – Layout – Construction – Process
economics – Materials of construction – Effluent treatment – Solvent recovery for fine
chemicals – Bulk drugs.
UNIT III BASE CHEMICAL PRODUCTION 12
Industrial Production of following base chemicals – Mineral acids (sulpuric acid, nitric
acid, phosphoric acid) – Naphthalene – Ammonia – Caustic soda – Industrial alcohol –
Butyl alcohol – Benzene – Phenol.
UNIT IV DRUG INTERMEDIATES AND FINE CHEMICAL PRODUCTION 12
Manufacture of following chemicals and their applications – Urea – Acrylonitrile –
Ethylacetate – Butadiene – Quinoline – Aniline – Tetrahydrofuran – Titaniumdioxide –
Vanillin.
UNIT V BULK DRUGS 12
Raw Materials – Production Techniques – Reaction Flow Sheet – Equipments – Utilities
for the production of drugs below – Paracetamol – Aspirin – Ibuprofen – Diazepam –
Darvon – Niacinamide – Chloramphenicol.
TOTAL: 60 PERIODS
TEXT BOOKS
1. Gopal Rao, M. and Sittig, M., “Dryden’s Outlines of Chemical Technology”, 3rd
Edition, Affiliated East West Press Pvt. Ltd., 2001.
2. Austin, G.T., “Shreve’s Chemical Process Industries”, 5th Edition, McGraw Hill
Book Company, 1984.
REFERENCES
1. Moulijin, J.A., Makkee, M. and Diepan, A.V., “Chemical Process Technology”,
John Wiley and Sons, 2001.
2. Shah, K.M., “Hand Book of Industrial Chemistry”, Vol. I and II, Multi-Tech
Publishing Co, 1999.
3. Pandey, G.N., “A Text Book of Chemical Technology”, Vol. II, Vikas Publishing
House (P) Ltd., 2000.
CH3405 TECHNOLOGY OF FINE CHEMICALS AND BULK DRUGS
UNIT I INTRODUCTION OF FINE CHEMICALS AND BULK DRUGS 12
Concept of fine and Bulk drugs and their salient features – Evolution of process –
Process chemistry – Research and development strategies in pharmaceutical industries.
UNIT II PRODUCTION, PLANNING AND CONTROL 12
Flow sheets – Types of flow sheets – Flow symbols – Line symbols – Concept of all
purpose and multipurpose plants – Plant design – Layout – Construction – Process
economics – Materials of construction – Effluent treatment – Solvent recovery for fine
chemicals – Bulk drugs.
UNIT III BASE CHEMICAL PRODUCTION 12
Industrial Production of following base chemicals – Mineral acids (sulpuric acid, nitric
acid, phosphoric acid) – Naphthalene – Ammonia – Caustic soda – Industrial alcohol –
Butyl alcohol – Benzene – Phenol.
UNIT IV DRUG INTERMEDIATES AND FINE CHEMICAL PRODUCTION 12
Manufacture of following chemicals and their applications – Urea – Acrylonitrile –
Ethylacetate – Butadiene – Quinoline – Aniline – Tetrahydrofuran – Titaniumdioxide –
Vanillin.
UNIT V BULK DRUGS 12
Raw Materials – Production Techniques – Reaction Flow Sheet – Equipments – Utilities
for the production of drugs below – Paracetamol – Aspirin – Ibuprofen – Diazepam –
Darvon – Niacinamide – Chloramphenicol.
TOTAL: 60 PERIODS
TEXT BOOKS
1. Gopal Rao, M. and Sittig, M., “Dryden’s Outlines of Chemical Technology”, 3rd
Edition, Affiliated East West Press Pvt. Ltd., 2001.
2. Austin, G.T., “Shreve’s Chemical Process Industries”, 5th Edition, McGraw Hill
Book Company, 1984.
REFERENCES
1. Moulijin, J.A., Makkee, M. and Diepan, A.V., “Chemical Process Technology”,
John Wiley and Sons, 2001.
2. Shah, K.M., “Hand Book of Industrial Chemistry”, Vol. I and II, Multi-Tech
Publishing Co, 1999.
3. Pandey, G.N., “A Text Book of Chemical Technology”, Vol. II, Vikas Publishing
House (P) Ltd., 2000.
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