PY3202 PHYSICAL PHARMACEUTICS SYLLABUS | ANNA UNIVERSITY B.TECH PHARMACEUTICAL TECHNOLOGY 3RD SEMESTER SYLLABUS REGULATION 2008 2011-2012 BELOW IS THE ANNA UNIVERSITY THIRD SEMESTER B.TECH PHARMACEUTICAL TECHNOLOGY DEPARTMENT SYLLABUS IT IS APPLICABLE FOR ALL STUDENTS ADMITTED IN THE YEAR 2011-2012 (ANNA UNIVERSITY CHENNAI,TRICHY,MADURAI,TIRUNELVELI,COIMBATORE), 2008 REGULATION OF ANNA UNIVERSITY CHENNAI AND STUDENTS ADMITTED IN ANNA UNIVERSITY CHENNAI DURING 2009
PY3202 PHYSICAL PHARMACEUTICS
UNIT I MICROMERITICS 12
Particle size and size distribution – Methods of determining particle size – Particle shape
and surface area – Methods of determining surface area pore size and derived
properties of powders.
UNIT II RHEOLOGY 12
Newtonian systems – Non newtonian systems – Plastic flow – Pseudo plastic flow –
Dilatant flow – Thixotropy – Viscometers – Types of viscometers.
UNIT III COLLOIDS 12
Electrical and optical properties of colloids – Sedimentation – Stokes law – Stability of
colloidal dispersions – Protective colloids – Sensitization of colloidal system –
Applications of colloids in pharmacy.
UNIT IV SUSPENSIONS AND EMULSIONS 12
Interfacial properties of suspended particles – Settling in suspensions – Formulation of
suspensions – Theories of emulsification – Physical stability of emulsions – Preservation
of emulsions – Rheologic properties of emulsions – Special emulsion system.
UNIT V DRUG STABILITY 12
Chemical degradation of pharmaceutical products – Hydrolysis, oxidation, isomerization,
polymerization, decarboxylation – Physical factors influencing chemical degradations –
Temperature, moisture, light, radiation – Factors influencing and methods of reducing
chemical degradation – Physical degradation of pharmaceutical products – Accelerated
stability testing.
TOTAL: 60 PERIODS
TEXT BOOKS
1. Martin, A., “Physical Pharmacy”, 4th Edition, Lippincott Williams and Wilkins,
B.I. Publications, 2002.
2. Derle, D.V., “Essentials of Physical Pharmacy”, 1st Edition, Pharma Book
Syndicate, 2006.
REFERENCES
1. Copper and Gunns, “Tutorial Pharmacy”, 6th Edition, CBS Publishers, 2005.
2. Bentley’s, “Text book of Pharmaceutics”, 1st Edition, AITBS Publishers, 2006.
3. Shotton, E., “Physical Pharmaceutics”, 1st Edition, Pharma Book Syndicate,
2007.
PY3202 PHYSICAL PHARMACEUTICS
UNIT I MICROMERITICS 12
Particle size and size distribution – Methods of determining particle size – Particle shape
and surface area – Methods of determining surface area pore size and derived
properties of powders.
UNIT II RHEOLOGY 12
Newtonian systems – Non newtonian systems – Plastic flow – Pseudo plastic flow –
Dilatant flow – Thixotropy – Viscometers – Types of viscometers.
UNIT III COLLOIDS 12
Electrical and optical properties of colloids – Sedimentation – Stokes law – Stability of
colloidal dispersions – Protective colloids – Sensitization of colloidal system –
Applications of colloids in pharmacy.
UNIT IV SUSPENSIONS AND EMULSIONS 12
Interfacial properties of suspended particles – Settling in suspensions – Formulation of
suspensions – Theories of emulsification – Physical stability of emulsions – Preservation
of emulsions – Rheologic properties of emulsions – Special emulsion system.
UNIT V DRUG STABILITY 12
Chemical degradation of pharmaceutical products – Hydrolysis, oxidation, isomerization,
polymerization, decarboxylation – Physical factors influencing chemical degradations –
Temperature, moisture, light, radiation – Factors influencing and methods of reducing
chemical degradation – Physical degradation of pharmaceutical products – Accelerated
stability testing.
TOTAL: 60 PERIODS
TEXT BOOKS
1. Martin, A., “Physical Pharmacy”, 4th Edition, Lippincott Williams and Wilkins,
B.I. Publications, 2002.
2. Derle, D.V., “Essentials of Physical Pharmacy”, 1st Edition, Pharma Book
Syndicate, 2006.
REFERENCES
1. Copper and Gunns, “Tutorial Pharmacy”, 6th Edition, CBS Publishers, 2005.
2. Bentley’s, “Text book of Pharmaceutics”, 1st Edition, AITBS Publishers, 2006.
3. Shotton, E., “Physical Pharmaceutics”, 1st Edition, Pharma Book Syndicate,
2007.
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